Santiago to La Serena | Buy your bus tickets on kupos.cl
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How to travel by bus from Santiago to La Serena?
From Santiago you can get to the city of La Serena by land with a large number of bus lines like: Andimar VIP, Pullman Bus, Expreso Norte, Ciktur, Buses Romani, Cormar Bus, Cóndor Bus, Turbus, Cikbus Elite, Los Corsarios, Serena Mar and other companies that will be willing to provide the best and most comfortable service through kupos.cl. From Santiago, the bus companies leave from the Sur Terminal, San Borja Terminal and the Alameda Terminal.
When you arrive in La Serena you will find the La Serena Bus Terminal and La Florida Aerodrome, which will allow you to travel to different cities in the country such as Iquique, Arica and Calama.
Why book a bus from Santiago to La Serena with kupos.cl?
The kupos.cl team is constantly improving, to offer a quality service to all the people who choose us. We want to be the platform where you find all the transport options to arrive and move around in your destinations and make your trip a pleasant experience. In kupos.cl you can find the available routes to transport you to and from La Serena. Compare and choose now!
About Santiago
Santiago, the capital of Chile, is a city located in the central region of the country, it has a large number of attractions and is considered the focus of the country's economic activity. Over time it has been reaching a series of milestones that have allowed it to stand out among other countries, such as having the fifth best economy and being the seventh most populated city in Latin America, the Santiago Metropolitan Park with its 722 hectares is the largest in Latin America, while the Gran Torre Santiago is the tallest skyscraper in South America.
About La Serena
La Serena is a city located in the north of Chile, in the Coquimbo Region. It is highly visited and considered one of the main tourist centers in the country. One of the elements that make the difference in the area is the neocolonial style architecture, the old Gabriela Mistral building, currently the headquarters of the Ministerial Secretary of Education, is considered a heritage of the region. The Archaeological Museum of La Serena, La Casa de las Palmeras, the Regional Library and the Monumental Lighthouse are just some of the tourist and culturally important places that La Serena has to offer.
Buses from Santiago to La Serena
Bus ticket prices according to type of seat
CLP$ 15.000
CLP$ 12.900
CLP$ 10.320
General Information
Main bus operators from Santiago to La Serena
Frequently Asked Questions
How many bus companies offer services from Santiago to La Serena?
In Chile there are 10 bus companies offering regular services from Santiago to La Serena.
Which bus companies offer services from Santiago to La Serena?
Turbus, Cikbus, Cormar Bus, Pullman Bus, Pullman San Andrés, Buses Romani, Ramos Cholele, Paravías, Cóndor Bus, Serena Mar
How do I buy the cheapest bus ticket from Santiago to La Serena online?
At kupos.cl we let you compare prices, schedules and services from most bus companies in Chile online. You can visit kupos.cl or download our app and buy your tickets in the easiest and most convenient way for you, using cash, debit or credit card, PayPal, etc. You can also buy your tickets directly on the bus company's website.
How much does the cheapest bus ticket from Santiago to La Serena cost?
The cheapest bus ticket from Santiago to La Serena costs CLP$ 10.320, and is available on August 20, 2026 at kupos.cl.
Which bus company offers the cheapest bus ticket from Santiago to La Serena?
Buses Romani offers the cheapest bus ticket from Santiago to La Serena, in a Semi cama seat for CLP $ 10.500, to travel on August 20, 2026 at kupos.cl.
What is the distance between Santiago and La Serena, and how long does the bus trip take?
The distance between Santiago and La Serena is 470 Kms, and the bus trip can take a minimum of 07 hours.
What are the earliest and latest departures available to travel by bus from Santiago to La Serena?
The earliest departure to travel by bus from Santiago to La Serena is at 06:10 and is offered by Turbus
The latest departure to travel by bus from Santiago to La Serena is at 23:59 and is offered by Serena Mar.
Which companies are most recommended for travelling by bus from Santiago to La Serena?
According to reviews and ratings from kupos.cl users, the three best companies for travelling by bus from Santiago to La Serena are: Rating Turbus, (4.1* based on 3456 ratings), Rating Cikbus, (3.2* based on 7935 ratings), Rating Cormar Bus, (4.3* based on 3146 ratings), Rating Pullman Bus, (3.5* based on 18763 ratings), Rating Pullman San Andrés, (3.9* based on 5249 ratings), Rating Buses Romani, (3.1* based on 1672 ratings), Rating Ramos Cholele, (2.7* based on 492 ratings), Rating Paravías, (3.1* based on 5316 ratings), Rating Cóndor Bus, (4.3* based on 3456 ratings), Rating Serena Mar, (3.6* based on 5990 ratings),
What is the price of a bus ticket from Santiago to La Serena for each seat type?
On buses from Santiago to La Serena a Salon cama seat costs around CLP$15.000, a Semi cama seat costs around CLP$12.900, a Semi cama low seat costs around CLP$10.320, a Salon cama low cost seat costs around CLP$12.000, a Salon cama individual seat costs around CLP$16.000, a Premium 180 seat costs around CLP$29.900, a Salon cama ind seat costs around CLP$17.510, a Salón cama seat costs around CLP$10.900, a Salón cama (i) seat costs around CLP$17.150,
What amenities do the buses operating from Santiago to La Serena have?
Generally, buses travelling from Santiago to La Serena have the following features and amenities: phone charger, WiFi, air conditioning, television, coffee, among others.


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