14 results found for this route.
Between Valparaíso and La Serena there is a road of a little more than 430 kilometers, on your way through Route 5 you will pass through many cities such as Totoralillo, Maitencillo, La Calera and Quillota.
The bus trip between Valparaíso and La Serena is very simple, since you don't need to make any kind of stop to get to your destination, some of the companies that can take you from the Bus Terminal in Valparaíso to the Bus Terminal in La Serena are Cóndor Bus, Turbus and Pullman Bus.
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We have all the means of land transport at your disposal, since we are a company that works daily to connect you with the best options in the environment. In kupos.cl you can find the best offers, compare prices between different alternatives and choose the one that best suits you.
Valparaíso is a colorful city that appears in the form of a natural amphitheater, surrounded by mountains and the bay that bears the same name.
Its striking construction and cultural richness have given it, since 2003, a position within the World Heritage Sites. Whether you prefer to spend a vacation by the sea or explore the urban panorama, Valparaíso is the ideal place for you, its funiculars and colorful facades will leave you with a beautiful memory of the central coast of Chile.
The city of La Serena is located in a strategic point of the Coquimbo Region that allows its residents and visitors to take advantage of a wide range of landscapes and natural beauties.
In the heart of the city we can find the Museo Colonial Iglesia San Francisco, which preserves inside part of the religious heritage of the region. If you prefer an open-air panorama, you cannot miss the Gabriel Coll Park, which is the green lung of the city and is the ideal place to have a good time on its courts, have a picnic with the family and take walks along the natural landscape.
Cheaper alon-cama 
Cheaper emi-cama 
No Empresas: 3
Precio Maximo (CLP): $ 26.300
Primera Salidas al dia: 08:15 hrs
Distancia: 425 Kms
No Servicios: 14
Precio Minimo (CLP): $ 10.100
Ultima Salida del dia: 22:15 hrs
Duration: 07 HRS
sun, 16 Aug 2026
mon, 17 Aug 2026
tue, 18 Aug 2026
wed, 19 Aug 2026
Based on 3456 reviews Based on 1658 reviews Based on 3146 reviewsIn Chile there are 4 bus companies offering regular services from Valparaíso to La Serena.
Cóndor Bus, Buses Romani, Cormar Bus, Turbus
At kupos.cl we let you compare prices, schedules and services from most bus companies in Chile online. You can visit kupos.cl or download our app and buy your tickets in the easiest and most convenient way for you, using cash, debit or credit card, PayPal, etc. You can also buy your tickets directly on the bus company's website.
The cheapest bus ticket from Valparaíso to La Serena costs CLP$ 10.100, and is available on August 15, 2026 at kupos.cl.
Buses Romani offers the cheapest bus ticket from Valparaíso to La Serena, in a Salon cama seat for CLP $ 15.000, to travel on August 15, 2026 at kupos.cl.
The distance between Valparaíso and La Serena is 425 Kms, and the bus trip can take a minimum of 07 hours.
The earliest departure to travel by bus from Valparaíso to La Serena is at 08:15 and is offered by Cóndor Bus
The latest departure to travel by bus from Valparaíso to La Serena is at 22:15 and is offered by Cormar Bus.
According to reviews and ratings from kupos.cl users, the three best companies for travelling by bus from Valparaíso to La Serena are: Rating Cóndor Bus, (4.3* based on 3456 ratings), Rating Buses Romani, (3.1* based on 1658 ratings), Rating Cormar Bus, (4.3* based on 3146 ratings), Rating Turbus, (4.1* based on 3456 ratings),
On buses from Valparaíso to La Serena a Salon cama seat costs around CLP$15.000, a Semi cama seat costs around CLP$10.100,
Generally, buses travelling from Valparaíso to La Serena have the following features and amenities: phone charger, WiFi, air conditioning, television, coffee, among others.
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