23 results found for this route.
The city of La Serena is located 1064 kilometers from Calama, a route that can be done through Route 5 that connects both cities.
If you want to travel by bus, you can do it through the Turbus, Cikbus Elite, Ciktur and Cormar Bus lines. These buses depart from the Calama Bus Terminal and arrive at the La Serena Bus Terminal.
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Calama is located in the Province of El Loa in the Antofagasta Region, 1,537 kilometers from Santiago.
Thanks to its great potential, mining became the main economic activity of this commune, being here one of the largest open pit mines in the world.
It is a city known for its folkloric and cultural events, some of the best known are the Calamatón, the Month of Calama and the Patron Saint Festivities. From here you can access several tourist spots such as Cerro La Cruz, the Tatio Geysers and Alto Loa.
La Serena is a city located in the north of Chile, in the Coquimbo Region. It is highly visited and considered one of the most important tourist centers in the country.
Near the city is the Elqui Valley, which stands out for its mysticism, here you will find typical products of the area such as papayas, wines and piscos.
Some nearby attractions are Punta de Choros and Isla Damas, located kilometers north of La Serena, with beautiful beaches and greater proximity to nature. Within the city you can visit places such as the Archaeological Museum of La Serena, La Casa de las Palmeras, the Regional Library and the Monumental Lighthouse.
Cheaper alon-cama 
Cheaper alon-cama-ind 
Cheaper remium 
No Empresas: 4
Precio Maximo (CLP): $ 54.990
Primera Salidas al dia: 08:00 hrs
Distancia: 1100 Kms
No Servicios: 23
Precio Minimo (CLP): $ 36.720
Ultima Salida del dia: 21:55 hrs
Duration: 15 HRS
sun, 16 Aug 2026
mon, 17 Aug 2026
tue, 18 Aug 2026
wed, 19 Aug 2026
Based on 18763 reviews Based on 3146 reviews Based on 7897 reviews Based on 3456 reviewsIn Chile there are 4 bus companies offering regular services from Calama to La Serena.
Pullman Bus, Cormar Bus, Cikbus, Turbus
At kupos.cl we let you compare prices, schedules and services from most bus companies in Chile online. You can visit kupos.cl or download our app and buy your tickets in the easiest and most convenient way for you, using cash, debit or credit card, PayPal, etc. You can also buy your tickets directly on the bus company's website.
The cheapest bus ticket from Calama to La Serena costs CLP$ 36.720, and is available on August 15, 2026 at kupos.cl.
Pullman Bus offers the cheapest bus ticket from Calama to La Serena, in a Salon cama seat for CLP $ 39.140, to travel on August 15, 2026 at kupos.cl.
The distance between Calama and La Serena is 1100 Kms, and the bus trip can take a minimum of 15 hours.
The earliest departure to travel by bus from Calama to La Serena is at 08:00 and is offered by Pullman Bus
The latest departure to travel by bus from Calama to La Serena is at 21:55 and is offered by Turbus.
According to reviews and ratings from kupos.cl users, the three best companies for travelling by bus from Calama to La Serena are: Rating Pullman Bus, (3.5* based on 18763 ratings), Rating Cormar Bus, (4.3* based on 3146 ratings), Rating Cikbus, (3.2* based on 7897 ratings), Rating Turbus, (4.1* based on 3456 ratings),
On buses from Calama to La Serena a Salon cama seat costs around CLP$45.900, a Salon cama ind seat costs around CLP$41.200, a Premium seat costs around CLP$52.000, a Salon cama low cost seat costs around CLP$36.720, a Salon cama individual seat costs around CLP$46.900, a Semi cama seat costs around CLP$38.300,
Generally, buses travelling from Calama to La Serena have the following features and amenities: phone charger, WiFi, air conditioning, television, coffee, among others.
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