19 results found for this route.
From Calama, you can get to Santiago by land through Route 5, both cities are separated by about 1,530 km of travel. You can get bus tickets to Santiago from Calama with companies such as Expreso Norte, Pullman Bus, Ciktur, Turbus and Plusschile that have departures from the San Borja Terminal and the Alameda Terminal.
In our platform we present you with different transport alternatives to the traditional, such as carpool or shared car, a means of transport that will change the way you travel. This alternative helps reduce CO2 emissions and the cost of the trip. It is a way to get to your destination without polluting, in less time and spending much less money. Kupos.com works daily to be a platform where you can find all the ways to reach your destination and give you the best experience at each stage of the trip.
Calama is located in the northern sector of Chile, specifically in the El Loa Province of the Antofagasta Region.
The main economic activity of the city is mining, in fact, here is the largest open pit mine in the world, called Chuquicamata, where copper, gold and molybdenum are extracted.
Calama has an extreme desert climate, with low temperatures at night but high during the day. From here you can access various tourist spots such as Alto el Loa, where customs, typical dishes and religious beliefs from ancient times are preserved.
Santiago is the capital of Chile and also one of the six provinces that make up the Metropolitan Region, it is located in the central area of the country. It is a few hours away from other prominent cities such as Valparaiso and Viña del Mar.
Santiago is a large city, considered the seventh most populated in Latin America. It is located on the banks of the Mapocho River and also from many of its buildings you will be able to see the Andes Mountains that provide a great attraction to the city. It has an excellent temperate climate and long dry season throughout the year. Its historic center is characterized by its abundant colonial buildings, many of them the headquarters of various museums or government entities.
Cheaper alon-cama 
Cheaper alon-cama-ind 
Cheaper alon-cama-individual 
No Empresas: 5
Precio Maximo (CLP): $ 66.300
Primera Salidas al dia: 08:00 hrs
Distancia: 1567 Kms
No Servicios: 19
Precio Minimo (CLP): $ 46.100
Ultima Salida del dia: 21:30 hrs
Duration: 21 HRS
thu, 13 Aug 2026
fri, 14 Aug 2026
sat, 15 Aug 2026
sun, 16 Aug 2026
Based on 18763 reviews Based on 7875 reviews Based on 3146 reviews Based on 5249 reviews Based on 3456 reviewsIn Chile there are 5 bus companies offering regular services from Calama to Santiago.
Pullman Bus, Cikbus, Cormar Bus, Pullman San Andrés, Turbus
At kupos.cl we let you compare prices, schedules and services from most bus companies in Chile online. You can visit kupos.cl or download our app and buy your tickets in the easiest and most convenient way for you, using cash, debit or credit card, PayPal, etc. You can also buy your tickets directly on the bus company's website.
The cheapest bus ticket from Calama to Santiago costs CLP$ 46.100, and is available on August 12, 2026 at kupos.cl.
Pullman Bus offers the cheapest bus ticket from Calama to Santiago, in a Salon cama seat for CLP $ 49.440, to travel on August 12, 2026 at kupos.cl.
The distance between Calama and Santiago is 1567 Kms, and the bus trip can take a minimum of 21 hours.
The earliest departure to travel by bus from Calama to Santiago is at 08:00 and is offered by Pullman Bus
The latest departure to travel by bus from Calama to Santiago is at 21:30 and is offered by Turbus.
According to reviews and ratings from kupos.cl users, the three best companies for travelling by bus from Calama to Santiago are: Rating Pullman Bus, (3.5* based on 18763 ratings), Rating Cikbus, (3.2* based on 7875 ratings), Rating Cormar Bus, (4.3* based on 3146 ratings), Rating Pullman San Andrés, (3.9* based on 5249 ratings), Rating Turbus, (4.1* based on 3456 ratings),
On buses from Calama to Santiago a Salon cama seat costs around CLP$58.500, a Salon cama ind seat costs around CLP$51.500, a Salon cama individual seat costs around CLP$59.500, a Semi cama seat costs around CLP$46.100,
Generally, buses travelling from Calama to Santiago have the following features and amenities: phone charger, WiFi, air conditioning, television, coffee, among others.
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