Santa Cruz to Santiago | Buy your bus tickets on kupos.cl
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How to travel by bus from Santa Cruz to Santiago?
Santiago is 184 kilometers away from Santa Cruz, you can access the capital city through Route 5, and at kupos.cl we take you to the capital city with Buses Nilahue and MT Bus, you can also travel with the company Transantin. The trips to Santiago depart from the Santa Cruz Bus Terminal.
However, if you are looking for a new way to travel, we bring you the carpooling service, another alternative when you are looking to travel comfortably, safely and for less money.
Why book a bus from Santa Cruz to Santiago with kupos.cl?
Kupos.cl offers all ground transportation services in a much safer, more comfortable and reliable way, allowing users to reserve their tickets, plan and choose the means of transportation they prefer.
Security is an integral part of our service. At kupos.cl we give you the facility to compare services from different companies so that you can quote and buy in the easiest way.
About Santa Cruz
Santa Cruz is a city that is located in the Colchagua Valley, in the O'Higgins Region. The city has a Mediterranean climate, warm in summer and cold with frequent rains in winter. During the year the lands receive the water supply from the Tinguiririca River, which flows into Lake Rapel. The union of these environmental factors, climate, soil and water have allowed Santa Cruz to consolidate itself as an important agricultural center recognized for the production of wines and tours of its vineyards.
The city is characterized by its colonial architecture, still very well preserved. During your visit to Santa Cruz you cannot miss the Enjoy Colchagua Casino, the Colchagua Museum and the Carillon Clock which is located in the Plaza de Armas and which currently serves as a tourist information point.
About Santiago
Santiago is the center of development of the main economic activities of Chile, it is a cosmopolitan and hectic city, which easily reflects the history and culture of the country through its network of more than 20 museums and cultural centers, in addition, it has several heritage sites and galleries that you can visit during your visit to this city.
It has a pleasant temperate climate and prolonged dry seasons during the year, which is why it rarely rains in Santiago. It is the seventh most inhabited city in Latin America, being the most populated urban nucleus in the country.
Buses from Santa Cruz to Santiago
Bus ticket prices according to type of seat
Cheaper lasico CLP$ 6.500
Cheaper emi-cama CLP$ 6.500
Cheaper alon-cama CLP$ 5.200
General Information
No Empresas: 4
Precio Maximo (CLP): $ 8.600
Primera Salidas al dia: 04:30 hrs
Distancia: 0 Kms
No Servicios: 52
Precio Minimo (CLP): $ 5.200
Ultima Salida del dia: 19:10:00 hrs
Duration: 00 HRS
Next Dates
Most Economical Price
tue, 18 Aug 2026
wed, 19 Aug 2026
thu, 20 Aug 2026
fri, 21 Aug 2026
CLP$ 5.000
CLP$ 5.000
CLP$ 5.000
CLP$ 5.000
Main bus operators from Santa Cruz to Santiago
Based on 437 reviews Based on 10267 reviews Based on 7910 reviews Based on 18763 reviewsFrequently Asked Questions
How many bus companies offer services from Santa Cruz to Santiago?
In Chile there are 4 bus companies offering regular services from Santa Cruz to Santiago.
Which bus companies offer services from Santa Cruz to Santiago?
Expreso Santa Cruz, Transantin, Jet Sur, Pullman Bus
How do I buy the cheapest bus ticket from Santa Cruz to Santiago online?
At kupos.cl we let you compare prices, schedules and services from most bus companies in Chile online. You can visit kupos.cl or download our app and buy your tickets in the easiest and most convenient way for you, using cash, debit or credit card, PayPal, etc. You can also buy your tickets directly on the bus company's website.
How much does the cheapest bus ticket from Santa Cruz to Santiago cost?
The cheapest bus ticket from Santa Cruz to Santiago costs CLP$ 5.200, and is available on August 17, 2026 at kupos.cl.
Which bus company offers the cheapest bus ticket from Santa Cruz to Santiago?
Transantin offers the cheapest bus ticket from Santa Cruz to Santiago, in a Salon cama seat for CLP $ 5.200, to travel on August 17, 2026 at kupos.cl.
What is the distance between Santa Cruz and Santiago, and how long does the bus trip take?
The distance between Santa Cruz and Santiago is 0 Kms, and the bus trip can take a minimum of 00 hours.
What are the earliest and latest departures available to travel by bus from Santa Cruz to Santiago?
The earliest departure to travel by bus from Santa Cruz to Santiago is at 04:30 and is offered by Expreso Santa Cruz
The latest departure to travel by bus from Santa Cruz to Santiago is at 19:10:00 and is offered by Pullman Bus.
Which companies are most recommended for travelling by bus from Santa Cruz to Santiago?
According to reviews and ratings from kupos.cl users, the three best companies for travelling by bus from Santa Cruz to Santiago are: Rating Expreso Santa Cruz, (3.9* based on 437 ratings), Rating Transantin, (3.7* based on 10267 ratings), Rating Jet Sur, (3.2* based on 7910 ratings), Rating Pullman Bus, (3.5* based on 18763 ratings),
What is the price of a bus ticket from Santa Cruz to Santiago for each seat type?
On buses from Santa Cruz to Santiago a Clasico seat costs around CLP$6.500, a Semi cama seat costs around CLP$6.500, a Salon cama seat costs around CLP$5.200, a Ejecutivo seat costs around CLP$6.180, a Premium seat costs around CLP$8.600,
What amenities do the buses operating from Santa Cruz to Santiago have?
Generally, buses travelling from Santa Cruz to Santiago have the following features and amenities: phone charger, WiFi, air conditioning, television, coffee, among others.
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